Protocatechuic Acid Attenuates Trabecular Bone Loss in Ovariectomized Mice
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چکیده
منابع مشابه
Effect of pre- and post-surgery treatment with risedronate on trabecular bone loss in ovariectomized rats.
The purposes of the present study were to differentiate the effects of pre-surgery treatment with risedronate and post-surgery treatment with a reduced dosing frequency of risedronate on trabecular bone loss in ovariectomized rats and to determine whether post-surgery treatment with a reduced dosing frequency of risedronate would have a beneficial effect on trabecular bone loss after pre-surger...
متن کاملPycnogenol(®) treatment inhibits bone mineral density loss and trabecular deterioration in ovariectomized rats.
CONTEXT Pycnogenol(®) extracted from French maritime pine bark (Pinus pinaster Ait. subsp. atlantica) is functional for its antioxidant activity. OBJECTIVE To investigate the effects of Pycnogenol(®) on bone mineral density (BMD), trabecular microarchitecture and bone metabolism in ovariectomized (OVX) rats. MATERIALS AND METHODS Thirty Sprague-Dawley rats were randomized into 3 groups: SHA...
متن کاملPrevention of trabecular bone loss in the mandible of ovariectomized rats.
The effect of therapeutic agents on trabecular bone loss in the mandible was investigated in ovariectomized rats. Eighty-seven Wistar SPF female rats were ovariectomized (OVX) or given a sham operation (Sham), and maintained on a diet containing 0.1% calcium. Four weeks later, groups of OVX rats were treated with estriol (E3), calcitonin (CT), etidronate, or 2-carboxyethylgermanium sesquioxide ...
متن کاملBone Microstructure Osteoporosis Trabecular Bone EFFECT OF VITAMIN K2 ON 3-D TRABECULAR MICROARCHITECTURE IN OVARIECTOMIZED RATS
Introduction : Two types of vitamin K occur in nature: vitamin K1 (phylloquinone, 2-methyl-3-phytyl-1,4-naphthoquinone), which is derived from plants, and vitamin K2 (menaquinones), a series of vitamers with multiisoprene units at the 3-position. Vitamin K2 activates osteoblasts to enhance calcification, acts as a coenzyme of γ-carboxylase for the Gla protein, and is also reported to inhibit bo...
متن کاملCoadministration of puerarin (low dose) and zinc attenuates bone loss and suppresses bone marrow adiposity in ovariectomized rats.
AIMS Puerarin is a phytoestrogen that shows osteogenic effects. Meanwhile, zinc stimulates bone formation and inhibits bone resorption. The study aims to investigate the effects of coadministration of puerarin (low dose) and zinc on bone formation in ovariectomized rats. MATERIALS AND METHODS Co-administration or use alone of puerarin (low dose) and/or zinc were gavaged in OVX rats. The estro...
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ژورنال
عنوان ژورنال: Oxidative Medicine and Cellular Longevity
سال: 2018
ISSN: 1942-0900,1942-0994
DOI: 10.1155/2018/7280342